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The Next Chapter of Orthobiologics: JBJS Special Issue Now Available

Cover of the September 2, 2026 JBJS Special Issue on Orthobiologics

A new special issue of JBJS delves into the topic of orthobiologics. The September 2, 2026 special issue can be found at JBJS.org: JBJS Special Issue on Orthobiologics  

“Today, orthobiologics occupies a unique position within orthopaedic surgery. Few areas have generated as much enthusiasm, investment, controversy, and debate. At the same time, few fields hold greater potential to transform the treatment of sports injuries, osteoarthritis, tendon disorders, osteonecrosis, fractures, and other musculoskeletal conditions that continue to challenge traditional surgical and nonoperative approaches . . . As a field, orthobiologics now stands at a crossroads,” write Guest Editors Nicolas S. Piuzzi, MD, and Stuart B. Goodman, MD in their editorial, The Next Era of Orthobiologics: From Promise to Precision. “The articles assembled in this special issue of The Journal reflect both the opportunities and challenges facing the field.” 

Among articles in the new issue:

Expert Review

Peptide Therapeutics in Orthopaedics. Current Evidence and Future Directions 

Health Care Recommendations 

An International Expert Consensus Statement Defining the Best Practices and Areas of Uncertainty Concerning the Use of Orthobiologics 

Scientific Articles 

Prevascularized Bone Marrow-Derived Mesenchymal Stem Cell Sheets Promote Tendon-Bone Integration in Rotator Cuff Repair 

Lower Trapezius Transfer at the Time of Reverse Shoulder Arthroplasty with an Allograft-Prosthetic Composite Can Restore External Rotation 

Timing of Vascular Endothelial Growth Factor Inhibitor Reinitiation and Risk of Wound Complications in Spinal Metastasis Surgery 

Ethics in Practice 

Ethical Challenges in the Clinical Use and Commercialization of Orthobiologics 

A Global Perspective 

Viewpoints, commentaries, and more  

“Orthobiologics is at a pivotal moment in its evolution, with a unique opportunity to translate scientific innovation into meaningful improvements in patient care,” note the Guest Editors. “The promise remains substantial; the responsibility is equally great. Achieving the full potential of biologic therapies will require collaboration across scientists, clinicians, regulators, industry partners, and patients worldwide.” 

Access the issue at JBJS.org: JBJS Special Issue on Orthobiologics  

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Previously on OrthoBuzz:

Spotlight on Sports Medicine: New Special Issue of JBJS Now Available 

JBJS Celebrates a Comprehensive Relaunch of The Journal 

Join the Journal as We Chart a New Course, Together 

JBJS Now Accepting Submissions for New Article Types 

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