Recent findings related to bone loss and bone healing, among other important topics, are presented in the new JBJS Guest Editorial What’s New in Musculoskeletal
Category: Basic Science
![Hounsfield units on CT, as a function of time since lower extremity amputation, for the ambulatory and nonambulatory patients.](https://orthobuzz.jbjs.org/wp-content/uploads/2023/11/hoyt_fig2.png)
Patients who sustain major trauma are at risk of bone mineral density (BMD) loss, note Hoyt et al. in a new study in JBJS. After
![](https://orthobuzz.jbjs.org/wp-content/uploads/2023/08/Florio-VS-Still.jpg)
A video abstract is available with the new study by Florio et al. in JBJS: Dual Inhibition of the Wnt Inhibitors DKK1 and Sclerostin Promotes
![Box and whisker plots. Fig. 1-A Genes from OA risk allele studies and/or differential expression studies more highly expressed in the instability group. Fig. 1-B Genes from OA risk allele studies and/or differential expression studies more highly expressed in the OA group.](https://orthobuzz.jbjs.org/wp-content/uploads/2023/07/alee_fig1_3-20-23.png)
A new JBJS study presents novel data on gene expression in glenoid cartilage following shoulder instability. JBJS Deputy Editor for Social Media Dr. Matt Schmitz
![Directly positioned landmarks on the proximal femur, distal femur, proximal tibia, and distal tibia.](https://orthobuzz.jbjs.org/wp-content/uploads/2023/05/kuip_fig2_rev_2-6-23.png)
Editor-in-Chief Dr. Marc Swiontkowski discusses a new study from The Netherlands that presents a fully automatic method for assessing lower-limb alignment from computed tomography (CT)
![Blue-tinted photograph of a microscope and a beaker held by a gloved hand.](https://orthobuzz.jbjs.org/wp-content/uploads/2022/12/BasicScience.png)
Recent groundbreaking studies are summarized in the JBJS Guest Editorial “What’s New in Musculoskeletal Basic Science,” now available at JBJS.org. Here, we spotlight the 5
![Hematoxylin and eosin staining of allograft particulate implanted in 3-mm femoral defects at 10 weeks postoperatively.](https://orthobuzz.jbjs.org/wp-content/uploads/2022/10/cohe_fig6.jpg)
The findings of a new animal study suggest that bisphosphonate treatment in donors may indeed be relevant when mineralized allografts are used in orthopaedic procedures.
![Bar graph depicting noise levels during cast removal using a quiet cast saw](https://orthobuzz.jbjs.org/wp-content/uploads/2022/08/shaw_fig1.jpg)
A new study in JBJS examines noise levels during cast removal. In this post, JBJS Editor-in-Chief Dr. Marc Swiontkowski reflects on the importance of research
![Render of Hip Dysplasia](https://orthobuzz.jbjs.org/wp-content/uploads/2022/06/hip-dysplasia-Ng-et-al.jpg)
Hip dysplasia is known to cause early joint deterioration, instability, and pain. It can be corrected with the Bernese periacetabular osteotomy (PAO). However, stability of
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Surgical site infections (SSIs) can be devastating complications for orthopaedic patients. A new study published in Nature advances our understanding of drug-resistant pathogens that can