Anteroposterior and lateral radiographs following excisional debridement of the nonunion site, placement of antibiotic cement spacer, and internal fixation with a medullary tibial nail and fibular titanium elastic nail.

What’s New in Limb Lengthening and Deformity Correction 2025

The latest research in limb lengthening and deformity correction is covered in the new JBJS Guest Editorial What’s New in Limb Lengthening and Deformity Correction. Here, we present the 5 most compelling studies, as selected by coauthor Jill C. Flanagan, MD, FAAOS. 

Basic Science

The pattern of bone formation during intramedullary lengthening of goat tibiae was analyzed in a pilot study using plain radiographs, micro-computed tomography, and histology. The researchers identified a new “inner zone” observed on histological sections of regenerate bone1. 

Limb Lengthening

In a single-center study that included 420 patients, researchers investigated the incidence of surgical site infection (SSI) following femoral and/or tibial lengthening with magnetic intramedullary lengthening nails. The rates of SSI and deep infection were 3.3% and 2.9%, respectively. Among patients with an infection, osteomyelitis and a history of limb lengthening via an external fixator were common2. 

Trauma

Researchers assessed the mid- to long-term outcomes in 225 patients with Gustilo-Anderson type III-B open tibial fractures treated with an Ilizarov ring fixator and an orthoplastic approach. Circular frames were used for a mean of 6.4 months. The deep infection rate (the primary outcome) was 3.5%. Union was achieved in 98.2% of patients3. 

Bone Defects

JBJS Case Connector published the first report of the use of automated struts for balanced cable trifocal bone transport. The patient was a 14-year-old boy with a 10.5-cm bone defect. The study authors concluded that “automated balanced cable transport is a viable option for segmental bone defects”4. 

Osseointegration

Outcomes at a minimum of 2 years of follow-up were reported in a study of 21 patients undergoing transtibial osseointegration for socket prosthesis-related issues following traumatic amputation. Significant improvements in function and prosthesis use were observed. Three patients underwent a total of 4 reoperations for soft-tissue-related issues, and 1 implant was removed5. 

What’s New in Limb Lengthening and Deformity Correction is freely available at JBJS.org. 

What’s New by Subspecialty

Each month, JBJS publishes a review of the most pertinent studies from the orthopaedic literature in a select subspecialty. To read the reports, visit the What’s New by Subspecialty collection at JBJS.org. 

Recent OrthoBuzz posts include: What’s New in Orthopaedic Trauma, What’s New in Spine Surgery, and What’s New in Foot and Ankle Surgery. 

Image reproduced from: Haruno LS, Owen JK, Marecek GS. Automated balanced cable trifocal bone transport: a case report. JBJS Case Connect. 2024 Dec 12;14(4). 


References 

  1. Bafor A, Isler A, Sprangel K, McBride-Gagyi S, Iobst CA. Qualitative and quantitative assessment of the regenerate bone formed during intramedullary limb lengthening using a goat (caprine) tibia model: a pilot study. J Limb Lengthening Reconstr. 2024 Jul-Dec;10(2):78-85. 
  2. Bains SS, Dubin JA, Green C, Herzenberg JE, McClure PK. Infection rates and risk factors with magnetic intramedullary lengthening nails. J Orthop. 2024 Apr 18;55:124-8. 
  3. Madhvani KR, Fong A, Clark T, Eng K, Condurache C, McGregor-Riley J, Shields DW. Mid to long-term outcomes of Grade III-B open tibial fractures definitively managed with a circular frame: a 13-year prospective database study at a major trauma center. J Orthop Trauma. 2024 Aug 1;38(8):447-51. 
  4. Haruno LS, Owen JK, Marecek GS. Automated balanced cable trifocal bone transport: a case report. JBJS Case Connect. 2024 Dec 12;14(4). 
  5. Muderis MA, Tan YC, Lu W, Tetsworth K, Axelrod D, Haque R, Akhtar MA, Roberts C, Doshi K, Al-Jawazneh S, Hoellwarth JS. Transtibial osseointegration following unilateral traumatic amputation: an observational study of patients with at least two years follow-up. Injury. 2024 Jun;55(6):111568. 

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