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Category: Basic Science

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Basic Science Trauma Video Summary

Video Abstract: Dual Inhibition of DKK1 and Sclerostin in Fracture Repair in Experimental Study in Nonhuman Primates

August 3, 2023August 2, 2023 OrthoBuzz for Surgeons

A video abstract is available with the new study by Florio et al. in JBJS:  Dual Inhibition of the Wnt Inhibitors DKK1 and Sclerostin Promotes

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Box and whisker plots. Fig. 1-A Genes from OA risk allele studies and/or differential expression studies more highly expressed in the instability group. Fig. 1-B Genes from OA risk allele studies and/or differential expression studies more highly expressed in the OA group.
Basic Science Editor's Choice Shoulder Sports Medicine

Shoulder Instability and Osteoarthritis: New Biological Insight

July 15, 2023July 12, 2023 OrthoBuzz for Surgeons

A new JBJS study presents novel data on gene expression in glenoid cartilage following shoulder instability. JBJS Deputy Editor for Social Media Dr. Matt Schmitz

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Directly positioned landmarks on the proximal femur, distal femur, proximal tibia, and distal tibia.
Basic Science Editor's Choice Foot and Ankle Hip Knee Orthopaedic Essentials

A New Method to Assist Surgical Decision-Making in Lower-Limb Alignment

May 4, 2023May 4, 2023 OrthoBuzz for Surgeons

Editor-in-Chief Dr. Marc Swiontkowski discusses a new study from The Netherlands that presents a fully automatic method for assessing lower-limb alignment from computed tomography (CT)

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Blue-tinted photograph of a microscope and a beaker held by a gloved hand.
Basic Science What's New

What’s New in Musculoskeletal Basic Science 2022

December 12, 2022December 8, 2022 OrthoBuzz for Surgeons

Recent groundbreaking studies are summarized in the JBJS Guest Editorial “What’s New in Musculoskeletal Basic Science,” now available at JBJS.org. Here, we spotlight the 5

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Hematoxylin and eosin staining of allograft particulate implanted in 3-mm femoral defects at 10 weeks postoperatively.
Basic Science Editor's Choice Trauma

Donor Bisphosphonate Treatment Negatively Impacts Mineralized Allografts, Animal Study Finds

October 6, 2022October 6, 2022 OrthoBuzz for Surgeons

The findings of a new animal study suggest that bisphosphonate treatment in donors may indeed be relevant when mineralized allografts are used in orthopaedic procedures.

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