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OrthoBuzz has published several posts about osteoporosis, fragility fractures, and secondary fracture prevention. In the May 17, 2017 edition of JBJS, Bogoch et al. add to evidence suggesting that a coordinator-based fracture liaison service (FLS) improves engagement with secondary-prevention practices among inpatients and outpatients with a fragility fracture.
The Division of Orthopaedic Surgery at the University of Toronto initiated a coordinator-based FLS in 2002 to educate patients with a fragility fracture and refer them for BMD testing and management, including pharmacotherapy if appropriate. Bogoch et al. analyzed key clinical outcomes from 2002 to 2013 among a cohort of 2,191 patients who were not undergoing pharmacotherapy when they initially presented with a fragility fracture.
- Eighty-four percent of inpatients and 85% of outpatients completed BMD tests as recommended.
- Eighty-five percent of inpatients and 79% of outpatients who were referred to follow-up bone health management were assessed by a specialist or primary care physician.
- Among those who attended the referral appointment, 73% of inpatients and 52% of outpatients received a prescription for anti-osteoporosis medication.
The authors conclude that “a coordinator-based fracture liaison service, with an engaged group of orthopaedic surgeons and consultants…achieved a relatively high rate of patient investigation and pharmacotherapy for patients with a fragility fracture.”
The May 17, 2017 edition of The Journal of Bone & Joint Surgery features a registry-based study by Mjaaland et al. comparing implant-survival/revision outcomes in total hip arthroplasty (THA) among four different surgical approaches:
- Minimally Invasive (MI) Anterior (n=2017)
- MI Anterolateral (n=2087)
- Conventional Posterior (n=5961)
- Conventional Direct Lateral (n=11,795)
Although the authors analyzed a whopping 21,860 THAs from 2008 to 2013, the findings are limited by the fact that all of those procedures used an uncemented stem.
Overall, the revision rates and risk of revision with the MI approaches were similar to those of the conventional approaches. There was a higher risk of revision due to infection in THAs that used the direct lateral approach than in THAs using the other three approaches. “To our knowledge,” the authors write, “this finding has not been previously described in the literature, and we do not have an explanation for it.” The authors also found a reduced risk of revision due to dislocation in THAs that used the MI anterior, MI anterolateral, and direct lateral approaches, relative to those using the posterior approach.
While the authors found all-cause risk of revision to be similar among all four approaches, they note that the follow-up in the study was relatively short (mean of 4.3 years) and that “additional studies are needed to determine whether there are long-term differences in implant survival.”
The orthopaedic community worldwide—and especially those of us in the US, the nation most notorious for over-prescribing—has become very cognizant of the epidemic of opioid abuse. Ironically, the current problem was fueled partly by the “fifth vital sign” movement of 10 to 20 years ago, when physicians were encouraged (brow-beaten, in my opinion) to increase the use of opioid medications to “prevent” high pain scores.
Researchers internationally are now pursuing clarification on the appropriate use of these medications. The societal consequences of opioid addiction, which all too often starts with a musculoskeletal injury and/or orthopaedic procedure, have been well documented in the social-science and lay literature. In the May 17, 2017 issue of The Journal, Smith et al. detail an additional consequence to the chronic use of opioid drugs—the negative impact of preoperative opioids on pain outcomes following knee replacement surgery.
Approximately one-quarter of the 156 total knee arthroplasty (TKA) patients analyzed had had at least one preoperative opioid prescription. Patients who used opioids prior to TKA obtained less pain relief from the operation than those who had not used pre-TKA opioids. The authors also found that pain catastrophizing was the only factor measured that was independently associated with pre-TKA opioid use.
To be sure, we need to disseminate this information to the primary care community so they will be more judicious about prescribing these medications for knee arthritis. Additionally, knee surgeons should consider working with primary care providers to wean their TKA-eligible patients off these medications, with the understanding that chronic use preoperatively compromises postsurgical pain relief and functional outcomes.
We have previously published in The Journal the fact that the use of opioids is largely a cultural expectation that varies by country; physicians outside the US often achieve excellent postoperative pain management success without the use of these medications. My bottom line: We must continue to press forward to limit the use of opioid medications in both pre- and postoperative settings.
Marc Swiontkowski, MD
The JBJS Elite Reviewers Program publicly recognizes our best reviewers for their outstanding efforts. Reviewers who review 4 or more manuscripts per year, rarely decline an invitation to review a manuscript (responding within 48 hours), and complete highly graded reviews within 1 week are eligible for the program.
Here is a recently updated list of JBJS Elite Reviewers, with 12 new additions marked with asterisks:
Elite Reviewers receive the following benefits in recognition of their exemplary performance:
- No submission fees for papers of which the reviewer is the first author (for 12 months)
- Free CME credits for all reviews
- Free online access to all JBJS publications
- Name recognition on the masthead of The Journal
The May 3, 2017 issue of JBJS contains one more in a series of personal essays where orthopaedic clinicians tell a story about a high-impact lesson they learned that has altered their worldview, enhanced them personally, and positively affected the care they provide as orthopaedic physicians.
This “What’s Important” piece comes from Dr. Edward Farrar of Wenatchee Orthopaedics in Washington. In his powerful and inspiring essay titled “Lessons on Life, Death, and Disability,” Dr. Farrar explains how a serious bicycle accident in 2008 severed his spinal cord at the T4 level.
What happened after a long and arduous recovery that left him paraplegic, followed shortly thereafter by the death of his partner from a brain tumor? He returned to work and saw patients although he could no longer operate. In his words, “I became a better listener and realized how much this has helped my patients and me.”
One of the many things he has learned from his experiences so far: “We may not always find the meaning and purpose that we were searching for, yet meaning and purpose can find us.”
If you would like JBJS to consider your “What’s Important” story for publication, please submit a manuscript via Editorial Manager. When asked to select an article type, please choose Orthopaedic Forum and include “What’s Important:” at the beginning of the title.
Because they are personal in nature, “What’s Important” submissions will not be subject to the usual stringent JBJS peer-review process. Instead, they will be reviewed by the Editor-in-Chief, who will correspond with the author if revisions are necessary and make the final decision regarding acceptance.
The exact cause of osteonecrosis in the setting of developmental dysplasia of the hip (DDH) is unknown. However, some pediatric orthopaedists are concerned that DDH treatment in the absence of the ossific nucleus of the femoral head increases the risk of subsequent osteonecrosis. That concern has to be weighed against evidence that delayed DDH treatment may lead to more difficult reduction and potentially necessitate additional procedures.
In the May 3, 2017 issue of JBJS, Chen et al. performed a meta-analysis of cohort and case-control studies to clarify this potential “conflict of interests” in DDH treatment. Twenty-one observational studies were included. Of the 969 hips with an ossific nucleus present before reduction, 198 hips (20.4%) had eventual osteonecrosis events; among the 608 hips without an ossific nucleus, 129 (21.2%) had osteonecrosis events. The authors state that this difference “is neither clinically important nor [statistically] significant.”
A sub-analysis determined that the presence of the ossific nucleus was not associated with significantly decreased odds of osteonecrosis even among patients who later developed more severe (grades II to IV) osteonecrosis. Chen et al. also performed a “meta-regression” of studies with short- and long-term follow-ups, finding “no evidence for a protective effect of the ossific nucleus with either short or long-term follow-up.”
Although 11 of the 21 studies in the meta-analysis were deemed high quality and 10 were of moderate quality, the inherent limitations of a meta-analysis derived predominantly from retrospective data prompted the authors to call for “further prospective studies with long-term follow-up and blinded outcome assessors.” Nevertheless, these findings lend additional support to the belief that treatment for DDH should not be delayed based on the absence of the femoral head ossific nucleus.
OrthoBuzz regularly brings you a current commentary on a “classic” article from The Journal of Bone & Joint Surgery. These articles have been selected by the Editor-in-Chief and Deputy Editors of The Journal because of their long-standing significance to the orthopaedic community and the many citations they receive in the literature. Our OrthoBuzz commentators highlight the impact that these JBJS articles have had on the practice of orthopaedics. Please feel free to join the conversation by clicking on the “Leave a Comment” button in the box to the left.
One of the most challenging diagnoses for general orthopedic surgeons as well as fracture specialists is a fracture of the talar neck. The infrequency of displaced talar fractures means that orthopaedic residents receive relatively little training in this area. A pivotal JBJS article in 1978 focused attention on these vexatious injuries. “Fractures of the Neck of the Talus” by Canale and Kelly provides clinically useful information and does two things that are very difficult to do today:
- Follows patients for a long time (an average of nearly 13 years)
- Obtains direct evidence of outcomes by physical exam, one-on-one measurement, and long-term imaging.
This remarkable duration of follow-up, so important in determining the impact of treatment in musculoskeletal injury, is very difficult today as a result of overly enthusiastic privacy protections and a costly regulatory infrastructure.
This classic JBJS article capitalizes on other classics, such as those by Blair (1943) on talar body salvage and studies by Halliburton (1958) and Mulfinger (1970) on the anatomy of talar blood supply. While Mulfinger showed the vascular supply of the talus,1 that study did not link that information to clinical care. The study by Canale and Kelly provides insight into how our care for patients with these uncommon fractures affects outcomes. In addition, the relatively primitive state of art at the time for the operative treatment of talar fractures led to fear of infection, and limited understanding of the basics of fracture healing and underdeveloped implants for fixation steered many surgeons away from rigid fixation in favor of closed reduction and cast immobilization.
The authors identified 107 fractures treated over a 33-year period; they examined and obtained radiographs on 71 of those fractures in 70 patients at an average follow-up of almost 13 years. (Fourteen of the patients were followed for more than 20 years, and 5 were followed for more than 30 years.) The preferred treatment protocol was closed reduction and casting. A reduction with less than 5 mm of displacement and 5° of misalignment was considered adequate. Open reduction with internal fixation was performed when these criteria were not met.
To assess outcomes, the authors directly measured ankle and subtalar motion, assessed whether a limp was present, and asked patients to rate their pain. Long before “patient-reported outcome measures” was a recognized term, these authors recorded them. Only 59% of patients in this series achieved good or excellent outcomes. The authors identified the high morbidity of these injuries, including avascular necrosis in more than half and 25 who needed later surgical intervention. The authors also recommended against talectomy as a salvage procedure.
While hampered by relatively low-resolution imaging and outcome measures that don’t meet current standards of reproducibility, Canale and Kelly provided a great deal of information that focused attention on the importance of quality of reduction. In addition, the paper created an enduring fracture classification that paralleled complication rates and potential outcomes.
Bruce Sangeorzan, MD
JBJS Deputy Editor
- Mulfinger GL, Trueta J. The blood supply of the talus. J Bone Joint Surg Br. 1970 Feb;52(1):160-7
The estimated annual cost of surgical treatment for anterior cruciate ligament (ACL) ruptures in the US is $2 billion. Are ACL surgery patients—and the health care system—getting significant value for all that money spent?
In the May 3, 2017 issue of The Journal of Bone & Joint Surgery, Nwachukwu et al. set out to answer that question by retrospectively analyzing rates of return to play and satisfaction among 231 ACL-surgery patients (mean age of 27 years) who were followed for a mean of 3.7 years. The authors found that:
- 87% had returned to play at a mean of 10 months after surgery.
- 89% of the 171 athletes eligible to return to their prior level of competition did so.
- 85% said they were “very satisfied” with the outcome, and 98% stated they would have the surgery again.
Not surprisingly, patients were more likely to say they were “very satisfied” if they had returned to play.
The authors also found that the use of patellar tendon autograft increased the chance of returning to play, while preoperative participation in soccer or lacrosse decreased the likelihood of returning to play. Those who participated in basketball, football, skiing, and tennis had higher return-to-play rates than those who participated in the two aforementioned sports.
In addition, Nwachukwu et al. found that one-third of those who did not return to sports reported fear of reinjury as the reason. The authors encourage surgeons to understand that “psychological readiness, fear of reinjury, and mental resiliency influence the probability of an athlete returning to play.”
In her commentary, Elizabeth Matzkin, MD cautions readers to interpret the Level IV study’s findings cautiously. She calls for “better prospective, homogeneous studies” to more accurately assess which surgical graft types and specific sports are more or less likely to result in patients returning to play. Nevertheless, the study, she says, “forces us to look at the big picture: What can we do to make ACL [reconstruction] better for our patients?”
In 2015, JBJS launched an“article exchange” collaboration with the Journal of Orthopaedic & Sports Physical Therapy (JOSPT) to support multidisciplinary integration, continuity of care, and excellent patient outcomes in orthopaedics and sports medicine.
During the month of May 2017, JBJS and OrthoBuzz readers will have open access to the JOSPT article titled “Risk of Recurrence of Low Back Pain (LBP): A Systematic Review.”
In that systematic review, the authors found low quality and heterogeneity among studies of this topic. They concluded that “the available research does not provide robust estimates of the risk of LBP recurrence and provides little information about factors that predict recurrence in people recently recovered from an episode of LBP.”